Endocrine Abstracts

Background: In the last decades mini-invasive techniques have been proposed to reduce costs and complications of emithyroidectomy and thyroidectomy, both for benign nodular goiter and thyroid microcarcinoma, and image-guided laser and radiofrequency ablation are the most used.Purpose: To investigate short and long-term efficacy of image-guided laser and radiofrequency ablation as therapy options for benign nodular goiter.Methods: F...

Introduction: Cyclic Cushing’s syndrome (cCS) is a rare condition characterized by periods of excessive cortisol secretion (peaks), alternating with phases of eucortisolism (through). In most cases, cCS is caused by an ACTH-secreting pituitary tumor, while only few cases of cyclic ectopic ACTH secretion (cEAS) have been described.Case presentation: In February 2023, a 58-year-old woman was referred to our Endocrine Unit due to a 10-year history of r...

The bone strain index (BSI) is a marker of bone deformation based on a finite element analysis inferred from dual X-ray absorptiometry (DXA) scans, that has been proposed as a predictor of fractures in osteoporosis. BSI value represents the average equivalent strain in a skeletal site, assuming that a higher strain level (higher BSI) indicates a lower bone’s resistance to loads with consequent higher risk of fractures. BSI index is usually calculated for specific loading ...

Management of skeletal fragility in women with early breast cancer (BC) under hormone-deprivation therapies (HDTs) may be a challenge and it is still unknown whether anti-osteoporotic therapies could be active in preventing fractures in pre-menopausal women exposed to HDTs. In this real-world, multicenter study, we evaluated the effectiveness of bone-active drmgs and determinants of vertebral fractures (VFs) in 306 pre-menopausal women (mean age 47.15±5.09, range: 30-54) wi...